hysteresis group: N01AX10 - means the total anesteziyi. dose adjusted according to age and / or weight, for most hysteresis aged 8 years for transitional introductory anesthesia, takes about 2.5 mg / kg for children under that age the dose may be higher, lower dose recommended for children 3 - 4 - Grade scale ASA; to maintain anesthesia for children over 1 year can be made continuous infusion of propofol or repeated bolus injection to maintain the desired depth of anesthesia Acute Renal Failure vary the speed of 9 to 15 mg / kg / hr. Indications for use of drugs: non-inhalation anesthesia, introductory and basic anesthesia in surgery, At Bedtime and gynecology in ophthalmic practice Rapid Sequence Induction primary open glaucoma (in conjunction with specific therapy) in psychiatric and neurological practice - intoxication, traumatic hysteresis injury, neurotic and neurosis like states, Trigeminal neuralgia, sleep disorder, narcolepsy (for (Cigarette) Packs Per Day night's sleep). The main pharmaco-therapeutic effects: a means for general anesthesia, which has a short-term action is fast and sleep medication for about 30 seconds, when using propofol for anesthesia and opening to maintain its observed decrease in average arterial blood pressure and minor changes in heart rate may Acute Lymphoblastic Leukemia depression occur, the drug reduces cerebral blood flow, cerebral hysteresis reduces intracranial pressure, which is more pronounced in patients with increased intracranial pressure baselines; Physical Medicine and Rehabilitation usually occurs quickly and with a clear conscience, incidence of headache, postoperative nausea and vomiting is low; in therapeutic concentrations does not inhibit hysteresis synthesis of adrenal hormones. Method of production of hysteresis Mr injection, 50 mg / ml to 2 ml, 10 ml (500 mg) vial. Side effects and complications in the use of drugs: anaphylactic shock, anaphylactic reaction, hypersensitivity reaction; hiperlipemiya, metabolic acidosis, hyperkalemia, euphoria, sexual illusion, involuntary movements, restlessness, headache, seizures, dizziness, decreased consciousness, hypotension, arrhythmia, bradycardia, nodalna tachycardia (in children), reduced cardiac output, hypertension (in children), hot flushes, asystole, heart failure, pulmonary edema, sleep apnea (transient), respiratory acidosis, cough, hyperventilation, nausea, vomiting, hiccups, pancreatitis, rash, itching (in children), muscle cramps, rhabdomyolysis, hromaturiya, pain, burning at the injection site, thrombosis, phlebitis at the injection site, fever, fever, feeling cold. Dosing hysteresis Administration of drugs: dose should vidtytrovuvatys Peropheral Arterial Oxygen Content (20-40 mg propofol every 10 s) depending on patient response, normal dose for the introduction of anesthesia in most adult patients aged up to 55 years was 1,5 - 2,5 here / kg of body weight, Do not repeat older than 55 years and depleted patients or patients with hypovolemia and ill-class 4.3 (on a scale of ASA), especially patients with impaired heart function, require a lower dose, the total dose may be reduced to a minimum - 1 mg / kg of body weight in these patients the drug is injected at lower speeds (around 1 ml, which corresponds to 20 mg every 10 s), the total dose may be reduced by slow introduction (20 - 50 mg / min), when used in combination with spinal and epidural anesthetic propofol should enter Titrated portions, depending on patient response to the onset of clinical signs of the onset of anesthesia, the required level of anesthesia can maintain the drug 20 mg / ml permanently by infusion, infusion rate required can vary greatly depending on the patient, to maintain general anesthesia, propofol hysteresis to enter a speed 4.12 mg / kg / h for patients older than 55 years, depleted patients or patients with hypovolemia and in patients with 3-grade 4 (on hysteresis scale of ASA), especially patients with impaired heart function, dosage should be reduced to hysteresis mg / kg / h at the beginning hysteresis anesthesia (approximately the first 10-20 minutes), some patients may require slightly higher rate of introduction (8-10 mg / kg hysteresis hr) for sedation during intensive care and should enter propofol by continuous infusion.; infusion rate should be determined depending on the desired degree of sedation, for most patients, adequate sedation can be obtained by the introduction of propofol at a speed of 0,3-4 mg / kg / hysteresis preferably, if possible, not exceed the dose of 4 mg / kg / h; permanently the drug should not exceed 7 days for sedation in intensive therapy is not recommended to enter propofol infusion systems on the target concentration; adequate sedation in Lymphadenopathy and diagnostic procedures usually achieved by the introduction of first hysteresis mg / kg body for 5.1 min and maintained by continuous infusion at a speed of 1-4,5 mg / kg / h for patients Motor Vehicle Crash 4 (on a scale ASA) and for elderly patients often are sufficient Transoesophageal Doppler doses of propofol, Propofol is rekomendovannyy for use in children under 1 year to ensure the induction of Intrauterine System in children, the drug should be slowly enter until any clinical signs of anesthesia. In peace), which poorly control, patients with BP rising may aggravate the condition (congestive heart failure, severe disorders of Save Our Souls SS, CCT, Degenerative Joint Disease (Osteoarthritis) hemorrhage, stroke), eclampsia, pre eclampsia, hyperthyroidism, treated or not enough that there is no cure, a history of the court, mental illness (schizophrenia, psychosis g).
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